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with an extrapolated geometric mean IC50 of approximately 20 mM resulting in a predicted selectivity index of 166
407(6802):395-401
24)25/h1-9H
2R)-cyclohexane-1
Formula: C4H4FN3O
Benazepril Hydrochloride 269970 with an extrapolated geometric meanBenazepril Hydrochloride is the hydrochloride salt of benazepril, a carboxyl containing angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II, resulting in vasodilation. Benazeprilat also decreases angiotensin II induced aldosterone
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