Finding a Moltensteel Dragon, pumping it up at least 6 times, then turning it into Skithryx, the Blight Dragon for lethal Infect damage in the middle of combat is a classic, but there are plenty of other shenanigans if youre willing to explore the increasing pool of Dragons
Hitting two permanents and bringing them back immediately also opens this blue instant up to some shenanigans, like targeting Archaeomancer and Gilded Lotus which allows you to re-cast it infinitely
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Yugi transforms into Yami and says his catchphrase
Sadly, you dont get this trigger upon each Bird damaging your opponent, though this card would obviously be utterly bonkers if that were the case