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Make sure to add protective spells like Tamiyo's Safekeeping and Revitalizing Repast to prevent blowouts

It trades the burn damage on Eshki for general creature discounts, allowing you to cast creatures for far cheaper than normal

A 6/6 with reach, whenever a permanent enters the battlefield under its owner's control, they can put another permanent with a lesser or equal mana cost directly into play

You could let the opponent draw a card after removing their Creature if you want to soften the blow, or you could give that draw to another opponent (great in Archenemy situations)

As well as disabling lifegain, The Lord Of Pain lets you take the mana value of the first spell a player casts each turn and dish out that much damage to somebody else

The deck itself can destroy people another way