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4-c]pyridine-3-carboxamide
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It inhibits LSD1 in biochemical assay with an IC50 ~16 nM
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PIK-294 - CAS# 900185-02-6 size:2mg solid 4-c]pyridine-3-carboxamidePIK 294, CAS No. 900185 02 6, is a highly selective inihibitor of the phosphoinositide 3 kinase (PI3K) p110 with an IC50 value of 10 nM compared to IC50 values of 10 M, 490 nM and 160 nM for PI3K , respectively. PIK 294 has been used to help distinguish the unique roles of the various PI3 K isoforms. PIK 294 inhibited both chemokinetic and chemotactic CXCL8 induced migration. Product information CAS Number: 900185 02 6 Molecular Weight: 489. 53
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