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Blockade of A2AR signaling with AZD4635 could reduce tumor burden and enhance antitumor immunity
2016 Nov 8
220 nM (ULK2)
and included previously unreported phosphosites on BMP2K
a potent muscarinic receptor agonist
GLP-1R Antagonist 1 oxy-PEG2-alcohol Blockade of A2AR signaling withGLP 1R Antagonist 1 (compound 5d) is an orally active, CNS penetrant and non competitive antagonist of glucagon like peptide 1 receptor (GLP 1R), with an IC50 of 650 nM. Product information CAS Number: 488097 06 9 Molecular Weight: 440. 73 Formula: C16H11ClF6N4O2 Chemical Name: 7 (4 chlorophenyl) 1,3 dimethyl 5,5 bis(trifluoromethyl) 1H,2H,3H,4H,5H,8H [1,3]diazino[4,5 d]pyrimidine 2,4 dione Smiles:
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