Like any go-wide strategy (which is effectively what were doing here), the ideal scenario is to be turning each card into multiple bodies with token production
Its in line with White creatures + token makers, like Cloudgoat Ranger, that compare positively to Deranged Hermit in a modern context
Then each player sacrifices all other creatures they control that dont share a creature type with the chosen creature they control
While i take your point about sideboard specific cards i would class the blasts and disenchant very differently - one is a occasion maindeck card with very wide sideboarding potential while the other is very obviously a sideboard only colour hoser
Meanwhile, a few tables over, a Slickshot Show-Off brew might face off against a dedicated Simulacrum Synthesizer deck
Whenever you cast a blue, black, or red spell, you gain 1 life