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With any creature removal, Maze of Iths, the fact that Mishras can soak up 3 damage and RRR definitely hurts your mana base, I wouldnt play them if you want to win
Its final ability is what makes it a little scary, though, which is that for three mana, one of which is Blue, you tap it and each opponent mills a number of cards equal to their hand size
Say that Divine Sacrament is on the field buffing white creatures by +1/+1 and Esper Sentinel has a +1/+1 counter on it
(Treat phased-out creatures and anything attached to them as though they don't exist until their controller's next turn.) Target creature phases out
A great example being Faerie Mastermind, who can draw you cards but also wear auras and equipment or trigger Coastal Piracy effects to draw even more cards