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Exile is often been a place to temporarily hold cards for other abilities like suspend, adventure, and flicker effects

Her ability lets you play the top card of your library every time she attacks, and since Karlach lets her attack twice, that's two cards every turn

Again, not just yours, but everyone's

Stompy decks in Legacy use it to throw stax pieces like Blood Moon and Chalice of the Void into play early, but plenty of decks can make use of a land that puts them a full turn ahead on mana

Obviously, if you can get some poison on your opponent, it gets a lot better as one mana a turn to tap something often just feels like removal

Invasion of New Phyrexia / Teferi Akosa of Zhalfir Im a big fan of army-in-a-can cards