Think two Hopeless Nightmares, or maybe two Momentum Breakers, to deal with big creatures or take their cards
Since this is an enter the battlefield trigger, and Etali costs a hefty seven mana, youll want some protection to stop your opponents from countering your stuff
You can use the oozes tokens or Hanweir Garrisons tokens as sacrifice fodder, you can double their attack triggers with Isshin, Two Heavens as One theres just lots of places you can slot these cards into in the hopes of melding them into one massive threat
Creative intellectuals with a lot of aces up their sleeves
Most of the time, this means during your main phase when the stack is empty.
Pair it with a wheel effect or a big draw spell at the table and it can get ridiculous fast