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c-Met inhibitor INCB28060 selectively binds to c-Met
InChi: InChI=1S/C23H30O3/c1-8-26-23(24)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(25-7)20(6)19(21)5/h9-15H
3)51(66)15-14-16-52-58(4
Abiraterone (Abi) acetate is an ester prodrug of the anticancer agent Abiraterone
Lacosamide is discontinued (DEA controlled substance)
A-192621 - CAS# 195529-54-5 0228 c-Met inhibitor INCB28060 selectively bindsA 192621 is a potent, nonpeptide, orally active and selective endothelin B (ETB) receptor antagonist with an IC50 of 4. 5 nM and a Ki of 8. 8 nM. The selectivity of A 192621 is 636 fold higher than ETA (IC50 of 4280 nM and Ki of 5600 nM). A 192621 promotes apoptosis in PASMCs. A 192621 alos causes elevation of arterial blood pressure and an elevation in the plasma ET 1 level. Product information CAS Number: 195529 54 5 Molecular Weight: 558. 66