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FTI-277 Hydrochloride Size:Solid 10 mg which exhibits selectivity against related

SKU: 22309714996

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Description

which exhibits selectivity against related TRPV channels and calcium channels

disrupts microtubule organization in cells

resulting from the CYP3A4/5-mediated catalysis of tamoxifen

water insoluble

ID-8 (10 μM) stimulates ESCs proliferation in serum-free media for more than 1 month

FTI-277 Hydrochloride Size:Solid 10 mg which exhibits selectivity against relatedFTI 277 is a peptide mimetic of the COOH terminal Cys Val Ile Met of K Ras4B that inhibited potently FTase in vitro (IC50 = 500 pM) and was highly selective for FTase over geranylgeranyltransferase I (GGTase I) (IC50 = 50 nM). FTI 277, the methyl ester derivative of FTI 276, was extremely potent (IC50 = 100 nM) at inhibiting H Ras, but not the geranylgeranylated Rap1A processing in whole cells. Product information CAS Number: 180977 34 8 Molecular

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