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ML-00253764 (100 µM) decreases cAMP production induced by [NLE4
InChi: InChI=1S/C107H153N27O26/c1-57(2)42-70(123-93(147)71(43-58(3)4)124-95(149)74(47-64-33-35-66(138)36-34-64)121-86(141)52-115-91(145)60(7)118-100(154)78(55-135)128-98(152)77(49-84(109)139)125-94(148)72(44-59(5)6)127-103(157)89(61(8)137)130-99(153)76(119-85(140)50-108)48-65-51-114-68-27-16-15-26-67(65)68)92(146)117-54-88(143)131-38-20-31-82(131)105(159)134-41-21-32-83(134)106(160)133-40-18-29-80(133)101(155)116-53-87(142)120-73(45-62-22-11-9-12-23-62)96(150)129-79(56-136)104(158)132-39-19-30-81(132)102(156)126-75(46-63-24-13-10-14-25-63)97(151)122-69(90(110)144)28-17-37-113-107(111)112/h9-16
9b-trimethyl-7-(prop-1-en-2-yl)-1H
3-dihydro-1H-isoindol-4-yl]amino}acetamide
InChi: InChI=1S/C23H26N2O2/c26-21-11-14-23(22(27)24-21
3-Hydroxy Midostaurin - CAS# 179237-49-1 7895 ML-00253764 (100 µM) decreases cAMP3 Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS like tyrosine kinase 3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9. 8 M in culture medium and plasma, respectively. 3 Hydroxy Midostaurin is less selective but more cytotoxic than PKC412. Product information CAS Number: 179237 49 1 Molecular Weight: 600. 66 Formula: C36H32N4O5 Chemical Name: N [(2R,4S,5S,7R) 17 hydroxy 5 methoxy 7 methyl 19 oxo
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