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15-hexaen-8-yl (2Z)-2-methylbut-2-enoate
Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis
6 μM (n = 6)
InChiKey: SNEIUMQYRCDYCH-LURJTMIESA-N
InChi: InChI=1S/C24H27N7O2/c1-29-10-12-31(13-11-29)16-8-9-18(21(14-16)33-3)27-24-25-15-19-22(28-24)30(2)20-7-5-4-6-17(20)23(32)26-19/h4-9
SPI-112 pione 15-hexaen-8-yl (2Z)-2-methylbut-2-enoateSPI 112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor with IC50s of 1 M, 18. 3 M and 14. 5 M for SHP2, protein tyrosine phosphatase (PTP) and PTP1B, respectively. Product information CAS Number: 1051387 90 6 Molecular Weight: 468. 46 Formula: C22H17FN4O5S Chemical Name: 3 [2 (5 {[(4 fluorophenyl)methyl]sulfamoyl} 2 hydroxy 1H indol 3 yl)diazen 1 yl]benzoic acid Smiles:
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