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18 hours) and cell cycle arrest (20-50 μM
1-1000 nM) elicits Ca2+ influx in mouse and human TRPV4-expressing human embryonic kidney (HEK) cells (EC50 values of 18 and 2
77 μM at 48 and 72 h in MTT assay
InChi: InChI=1S/C21H18N4O2/c1-14-18(20(26)24(22-14)16-9-5-3-6-10-16)13-19-15(2)23-25(21(19)27)17-11-7-4-8-12-17/h3-13
InChiKey: ABDDQTDRAHXHOC-UHFFFAOYSA-N
DD-03-156 ope muscari 18 hours) and cell cycleDD 03 156 is a potent and selective degrader of CDK17 and LIMK2. The selectivity and potency of DD 03 156 is exquisite and makes an advanced starting point for the development of a chemical probe for the degradation of CDK17. Product information Molecular Weight: 1106. 31 Formula: C53H62F3N9O8S3 Smiles: