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C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29
Smiles: CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
2 mg/mL (8
Indometacin farnesil (IMF) is a newly synthesized prodrug of indomethacin designed to reduce the occurrence of side-effects by esterification of the carboxyl group of indomethacin with farnesol
cell growth inhibition is markedly enhanced compared with single-agent treatment
TAE-1 ethylbenzenesulfonate C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29IC50: 0. 3 0. 02 M for AChE; 3. 9 0. 2 M for BuChE TAE 1 is an inhibitor of amyloid fibril formation and aggregation. Alzheimers disease (AD), a progressive neurodegenerative disorder, is characterized by the cerebral accumulation of insoluble aggregates of amyloid peptides (A). Although the precise mechanisms governing neuronal loss remains ambiguous, toxicity resulting from A activated pathways is evident. In vitro: In a previous study, the authors
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