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leaving normal cells almost unaffected
Smiles: NC(=O)C1N=CN(C2OC(CO)C(O)C2O)C=1N
It is a good chemical tool to enable interrogation of GPR39 signaling in different cellular contexts
with antiallergic effects related to histamine antagonism
25(11):1349-52
CNX-1351 - CAS# 1276105-89-5 Catalog No.:M9803-10 leaving normal cells almost unaffectedCNX 1351 is a selective covalent Inhibitor of PI3K. In an end point assay, CNX 1351 potently inhibited PI3K and was 20400 times less potent against , , and . CNX 1351 inhibit PI3K signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX 1351 inhibits growth of cells dependent on PI3K. CNX 1351 also inhibits PI3K signaling in vivo and bonds to p110. Product information CAS Number: 1276105 89 5 Molecular
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