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NRX-252114 ncristine Molecular Weight: 1033

SKU: 99169745254

4.4
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Description

Molecular Weight: 1033

140898-91-5

which initiates translocation of β-Arr 1 by direct TSHR activation and potentiates TSH-mediated preosteoblast differentiation in vitro

Burslem et al (2018) The advantages of targeted protein degradation over inhibition: An RTK case study

Urolithin A exerts a dose- and time-dependent significant arrest at G2/M and S phases after treatments with 50 and 100 μM at 24 and 48 h compared to control cells

NRX-252114 ncristine Molecular Weight: 1033NRX 252114 is a potent enhancer of the interaction between catenin, and its cognate E3 ligase, SCF TrCP. NRX 252114 enhances the binding of pSer33 S37A catenin peptide for TrCP with an EC50 of 6. 5 nM and a Kd of 0. 4 nM. NRX 252114 induces mutant catenin degradation. Product information Molecular Weight: 510. 32 Formula: C22H12Cl2F3N3O2S Chemical Name: 2 {4 [(2,6 dichlorophenyl)sulfanyl] 2 oxo 6 (trifluoromethyl) 1,2 dihydropyridine 3 carbonyl} 2,3

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