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112(6):1839-44
Chemical Name: 2-(3-methoxyphenyl)acetic acid
Smiles: CC(C)(O)C1=CC=CC(=N1)N1C2=NC(NC3=CC4CN(C)CC5(CC5)C=4C=C3)=NC=C2C(=O)N1CC=C
InChi: InChI=1S/C23H28N2O3/c1-16-13-19-20(25-16)11-8-12-21(19)27-15-18(14-24-23(2
The heat shock element–binding activity reflects the activation of heat shock factor 1 in response to (5E
bis(7)-Tacrine Catalog No.:M22824-C 112(6):1839-44IC50: 0. 40 nM bis(7) Tacrine is an AChE inhibitor. Acetylcholinesterase ( AChE), the primary cholinesterase in the body, is an enzyme catalyzing the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. In vitro: bis(7) Tacrine, the 9 amino 1,2,3,4 tetrahydroacridine (THA) dimer, was identified as a promising drug candidate for the palliative treatment of Alzheimer's disease, due to its significant
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