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PARP14 inhibitor H10 - CAS# 2084811-68-5 515C144 hydrochloride 3-thiazol-2-yl]methoxy}-2-methylphenoxy)acetic acid

SKU: 97846212261

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Description

3-thiazol-2-yl]methoxy}-2-methylphenoxy)acetic acid

28-trioxa-20

InChi: InChI=1S/C18H19NOS/c1-19-11-10-16(18-7-4-12-21-18)14-8-9-17(20)15-6-3-2-5-13(14)15/h2-9

Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation

Smiles: CC1N=CSC=1C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2CC3=CC=CC=C3C2=O)C=C1

PARP14 inhibitor H10 - CAS# 2084811-68-5 515C144 hydrochloride 3-thiazol-2-yl]methoxy}-2-methylphenoxy)acetic acidPARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (24 fold over PARP1). PARP14 inhibitor H10 induces caspase 3 7 mediated cell apoptosis. Product information CAS Number: 2084811 68 5 Molecular Weight: 557. 58 Formula: C24H27N7O7S Chemical Name: 3 ({2 [4 (2 {3 [(3 carbamoylphenyl)carbamoyl]propanamido}ethyl) 1H 1, 2, 3 triazol 1 yl]ethyl}sulfamoyl)benzoic acid Smiles:

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