CHMFL-ABL-121 Catalog No.:M27849-C Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CCCC)=NC(Cl)=C2C(O)=O)C=1[2H]

Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CCCC)=NC(Cl)=C2C(O)=O)C=1[2H]

InChi: InChI=1S/C34H68N2O13/c1-33(2

Int Arch Allergy Immunol

Chemical Name: 5-[6-amino-5-(4-chlorophenyl)pyridin-3-yl]pyrimidin-2-amine

with 50% inhibitory concentrations <0

CHMFL-ABL-121 Catalog No.:M27849-C Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CCCC)=NC(Cl)=C2C(O)=O)C=1[2H]CHMFL ABL 121 is a highly potent type II ABL kinase inhibitor with IC50s of 2 nM and 0. 2 nM against purified inactive ABL wt and T315I kinase protein, respectively. Product information CAS Number: 2270879 07 5 Molecular Weight: 580. 67 Formula: C30H31F3N6OS Chemical Name: N {4 [(4 methylpiperazin 1 yl)methyl] 3 (trifluoromethyl)phenyl} 3 ({3 [(E) 2 (pyridin 2 yl)ethenyl] 1H indazol 6 yl}sulfanyl)propanamide Smiles: