Vinorelbine (ditartrate) Catalog No.:M9575-2 Smiles: CCCCOC1N=C(N)C2NC(=O)CN(CC3C=CC=C(CN4CCCC4)C=3)C=2N=1

Smiles: CCCCOC1N=C(N)C2NC(=O)CN(CC3C=CC=C(CN4CCCC4)C=3)C=2N=1

J Clin Pharmacol

201:249-57

and neuroblastoma xenograft each)

Smiles: C[C@@H](OC)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1C1NC2=CC(F)=C(C=C2N=1)[C@H]1CC[C@H](C2C=C3N=C(NC3=CC=2F)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC)N1C1C=C(F)C(=C(F)C=1)N1CCC(CC1)C1C=CC(F)=CC=1

Vinorelbine (ditartrate) Catalog No.:M9575-2 Smiles: CCCCOC1N=C(N)C2NC(=O)CN(CC3C=CC=C(CN4CCCC4)C=3)C=2N=1Vinorelbine is a semisynthetic vinca alkaloid derived from the leaves of the periwinkle plant (Vinca rosea) with antineoplastic activity. Vinorelbine binds to tubulin, thereby inhibiting tubulin polymerization into microtubules and spindle formation and resulting in apoptosis of susceptible cancer cells. Inhibition of mitotic microtubules correlates with antitumor activity, whereas inhibition of axonal microtubules seems to correlate with