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Although the exact multiple mechanisms of action through which this agent exerts its effects have yet to be fully elucidated
Chemical Name: 3-(azepane-1-sulfonyl)-N-(3-bromophenyl)benzamide
Formula: C21H20N2O3S
exhibiting ATP-competitive inhibition kinetics
InChiKey: BJFSUDWKXGMUKA-UHFFFAOYSA-N
ABT-888 dihydrochloride - CAS# 912445-05-7 0109 Although the exact multiple mechanismsABT 888 dihydrochloride, also known asVeliparib, CAS No. 912445 05 7, is a potent and selective Poly (ADP Ribose) Polymerase (PARP) Inhibitor. ABT 888 dihydrochloride enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT 888 dihydrochloride is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5. 2 and 2. 9 nM, respectively). Product information CAS Number: 912445 05 7
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