Most of the ligand-receptor interactions are hydrophobic with the exception of the contacts of the pyrimidine-amine group with the T815 7
InChiKey: DNCAZYRLRMTVSF-JTQLQIEISA-N
Smiles: OC1C=C2O[C@H]([C@@H](CC2=C(O)C=1)OC(=O)C1C=C(O)C(O)=C(O)C=1)C1=CC=C(O)C(O)=C1
H2O : ≥ 41 mg/mL (85
FT827 exclusively inhibit USP7 in a panel of 38 deubiquitinases (DUBs) from diverse families
Mal-amido-PEG9-NHS ester adecanedioic acid Most of the ligand-receptor interactionsMal amido PEG9 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2575631 92 2 Molecular Weight: 733. 76 Formula: C32H51N3O16 Chemical Name: 2,5 dioxopyrrolidin 1 yl 1 [3 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)propanamido] 3,6,9,12,15,18,21,24,27 nonaoxatriacontan 30 oate Smiles: O=C(CCN1C(=O)C=CC1=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O InChiKey: LAFXBPMISAOAEN UHFFFAOYSA N