) completely inhibits basal and 2-deoxy-D-glucose (2DG
suggesting that it was the BRD inhibition component of the compounds that mediated cytokine reduction
inhibits xenograft growth in a dose-dependent manner in nude mice
29)25(37-21)32-19-18-22(30)31-26(32)35/h9-10
InChi: InChI=1S/C66H95N11O13S/c1-11-42(6)58(64(86)75(9)51(40(2)3)37-53(90-44(8)78)63-72-50(39-91-63)60(83)70-48(35-43(7)65(87)88)36-45-21-14-12-15-22-45)74-61(84)52-24-17-19-34-77(52
Alpelisib hydrochloride - CAS# 1584128-91-5 Size:Contact [email protected] for quotation ) completely inhibits basal andAlpelisib hydrochloride (BYL 719 hydrochloride) is a potent, orally active, and selective PI3K inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110, p110, p110, and p110, respectively. Alpelisib hydrochloride (BYL 719 hydrochloride) shows antineoplastic activity. Product information CAS Number: 1584128 91 5 Molecular Weight: 477. 93 Formula: C19H23ClF3N5O2S Chemical Name: (2S) N1 {4 methyl 5 [2 (1,1,1 trifluoro 2 methylpropan 2 yl)pyridin