![AP-1/NF-κB activation inhibitor 1 Size:Contact sales@xcessbio.com for quotation 536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M15234_1631114892.gif?v=1631114894)
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536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2
increased pan-nuclear γ-H2AX staining occurs in a dose dependent manner
Upon oral administration
InChi: InChI=1S/C30H33N3O5S/c1-19-16-32(17-20(2)37-19)18-28(35)31-23-6-7-27-22(13-23)12-21-4-3-5-25(30(21)39-27)26-14-24(34)15-29(38-26)33-8-10-36-11-9-33/h3-7
18-trihydroxy-5
AP-1/NF-κB activation inhibitor 1 Size:Contact [email protected] for quotation 536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2AP 1 NF B activation inhibitor 1 is a potent AP 1 and NF B mediated transcriptional activation inhibitor (IC50=1 M), without blocking basal transcription driven by the actin promoter. AP 1 NF B activation inhibitor 1 has a similar inhibitory effect on the production of IL 2 and IL 8 levels in stimulated cells. Product information CAS Number: 188936 12 1 Molecular Weight: 344. 25 Formula: C13H11F3N4O4 Chemical Name: ethyl 4 [(3 methyl 2,5 dioxo 2,5
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