it was developed based on the structure of the Abl-imatinib complex to address imatinib intolerance and resistance
Chemical Name: 1'-{4-[1-(4-fluorophenyl)-1H-indol-3-yl]butyl}-3H-spiro[2-benzofuran-1
Tandospirone citrate is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2
Metarrestin (ML246) is an orally active and specific perinucleolar compartment (PNC) inhibitor that disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription
IL-8 release and neutrophil chemotactic activity as well as it increased IP-10 release and lymphocyte chemotactic activity
3'-Hydroxypterostilbene - CAS# 475231-21-1 Catalog No.:M12494-10 it was developed based on3' Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9. 0, 40. 2, and 70. 9 M for COLO 205, HCT 116, and HT 29 cells, respectively) by inducing apoptosis and autophagy. 3' Hydroxypterostilbene inhibits the PI3K Akt mTOR p70S6K, and p38MAPK pathways and activates the ERK1 2, JNK1 2 MAPK pathways. Product information CAS Number: 475231 21 1 Molecular Weight: 272. 30 Formula: