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PubMed Central PMCID: PMC5399287
5-dihydroxy-6-(hydroxymethyl)-2-{[7
3-c]pyridine-5-carboxylate
γ-Tocopherol (D-γ-Tocopherol) is well absorbed and accumulates to a significant degree in some human tissues
UCB1184197
YKL-5-124 TFA Catalog No.:M14492-2 PubMed Central PMCID: PMC5399287YKL 5 124 TFA is a potent, selective, irreversible and covalent CDK7 inhibitor with IC50s of 53. 5 nM and 9. 7 nM for CDK7 and CDK7 Mat1 CycH, respectively. YKL 5 124 TFA is >100 fold greater selective for CDK7 than CDK9 and CDK2, and inactive against CDK12 and CDK13. YKL 5 124 TFA induces a strong cell cycle arrest, inhibits E2F driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status. Product information