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Trimethylamine N-oxide is frequently found in the tissues of a variety of marine organisms that protects against the adverse effects of temperature
Formula: C27H31N7OS
Madrasin stalls spliceosome assembly at the A complex
is an investigational drug candidate for metastatic colorectal cancer
GSK 1014802
AGN-193931 6-2005 Trimethylamine N-oxide is frequently foundAGN 195183 is a potent and selective agonist of RAR(Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RAR . IC50 value: 3 nM (Kd); 200 nM (EC80, RAR Trans.) Compound 4(AGN 195183) inhibited the growth of breast cancer cell lines, and was inactive in an in vivo model of topical irritation. Compound 4 and ATRA inhibit growth of the human breast cancer cell lines, T 47D and SK BR 3, compound 4 does not cause the topical
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