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CP-724714 - CAS# 383432-38-0 Catalog No.:M10878-10 Receptor binding results in constriction

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Description

Receptor binding results in constriction of cranial vessels and inhibition of nociceptive transmission

NE 52-QQ57 significantly inhibited the AGE-induced increased expression of several key inflammatory cytokines and signaling molecules

Chemical Name: 5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid sodium

also known as ABT-888

Borowiak M

CP-724714 - CAS# 383432-38-0 Catalog No.:M10878-10 Receptor binding results in constrictionCP 724714 is An orally bioavailable quinazoline with potential antineoplastic activity. CP 724,714 selectively binds to the intracellular domain of HER2, reversibly inhibiting its tyrosine kinase activity and resulting in suppression of tumor cell growth. HER2, a member of the epidermal growth factor receptor (EGFR) family, is overexpressed in many adenocarcinomas, particularly breast cancers. Product information CAS Number: 383432 38 0 Molecular

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