Icenticaftor tor II Smiles: CC1=CC=C2C[C@@H](CCC2=C1CCC(O)=O)NS(=O)(=O)C1C=CC(Cl)=CC=1

Smiles: CC1=CC=C2C[C@@H](CCC2=C1CCC(O)=O)NS(=O)(=O)C1C=CC(Cl)=CC=1

Chemical Name: 2-{4'-carbamoyl-[1

It is a σ1 receptor agonist with 5% of its SRI potency

7-dioxaspiro[5

RANKL and OPG proteins expressions in relation to OVX group

Icenticaftor tor II Smiles: CC1=CC=C2C[C@@H](CCC2=C1CCC(O)=O)NS(=O)(=O)C1C=CC(Cl)=CC=1Icenticaftor (QBW251) is an orally active CFTR channel potentiator, with EC50s of 79 nM and 497 nM for F508del and G551D CFTR, respectively. Icenticaftor can be used for chronic obstructive pulmonary disease (COPD) and cystic fibrosis research. Product information CAS Number: 1334546 77 8 Molecular Weight: 361. 24 Formula: C12H13F6N3O3 Chemical Name: 3 amino 6 methoxy N [(2S) 3,3,3 trifluoro 2 hydroxy 2 methylpropyl] 5 (trifluoromethyl)pyridine 2