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ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line
Schaefer M
TRPM8 antagonist 2 potently inhibits menthol-induced increase in intracellular Ca2+ levels in Ca2+ fluorimetric assays in HEK293 cells stably expressing the rat isoform of TRPM8 channels (IC50
Giovanella BC
Brain-Permeable
RO2959 hydrochloride(x) - CAS# 1219927-22-6 Catalog No.:M12941-2 ML-7 amplifies the quinocetone-induced cellRO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 hydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1 Stim1 channels with an IC50 of 25 nM. RO2959 hydrochloride is also a potent inhibitor of human IL 2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways. Product information CAS Number: 1219927 22 6 Molecular
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