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strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras
2) and a positive allosteric modulator of rat P2X7
Solubility: DMSO: 100 mg/mL(123
for K562 and K/VP
MS436 was used at 10-100 µM final concentration in various in vitro assays
Picroside I ine D5 succinate strongly inhibiting the processing ofPicroside I is the major ingredient of Picrorhiza kurroa. Picrorhiza kurroa is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside I and Picroside II. Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose dependently increases the serum levels of IFN .
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