WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 Catalog No.:M60097-2S resulting in the proteasomal degradation

resulting in the proteasomal degradation of oncogenic client proteins

and p97/VCP

19:2260-73

resulting in inhibition of survivin antiapoptotic activity (via the extrinsic or intrinsic apoptotic pathways) and tumor cell apoptosis

CAS Number: 872511-34-7

WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 Catalog No.:M60097-2S resulting in the proteasomal degradationWS6, CAS No. 1421227 53 3, is a highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets, identified by a high throughput, cell based screening using rodent pancreatic cells. It can induce proliferation of mouse R7T1 cells with an EC50 ~0. 28 M, and induce up to 4% of rat cells and 3% of human cells to proliferate, with a similar EC50 of 0. 4 M. WS6 induces proliferation of primary rat