E3330 Catalog No.:M20512-C Smiles: N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)C1=CC=NC2=CC=C(C=C21)OCCCN1CCN(CC1)C(=O)CN(CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O)CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O

Smiles: N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)C1=CC=NC2=CC=C(C=C21)OCCCN1CCN(CC1)C(=O)CN(CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O)CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O

14 mg/mL(22

Formula: C30H44O7

InChi: InChI=1S/C25H22ClF3N6O3/c1-13-8-9-35(34-13)20-11-16(26)6-7-17(20)22(25(27

Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18

E3330 Catalog No.:M20512-C Smiles: N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)C1=CC=NC2=CC=C(C=C21)OCCCN1CCN(CC1)C(=O)CN(CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O)CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=OE3330 (APX 3330) is a direct, orally active and selective AP endonuclease 1 (APE1; REF 1) inhibitor, which suppresses NF B DNA binding activity. E3330 (APX 3330) blocks TNF induced activation of IL 8 production in liver cancer cell lines. E3330 (APX 3330) shows anticancer properties, such as inhibition of cancer cell growth and migration. Product information CAS Number: 136164 66 4 Molecular Weight: 378. 46 Formula: C21H30O6 Chemical Name: (2E) 2