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13 µM (72 h) in 5637 cells
C5H4N2O4/c18-10-3-1-9(2-4-10)15(26)13-11(19)5-8(6-12(13)20)7-25-16(21)14(17(22)27)23-24-25
Rats are sacrificed and tumors are harvested 15 days after treatment initiation
BAY-87-2243 prior to RT significantly reduced TCD50 from 123 to 100 Gy (p=0
Smiles: CCCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)C1=CC2OCCOC=2C=C1
3-Oxo-5β-cholanoic acid 8158471) 13 µM (72 h) in3 Oxo 5 cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORt (Kd=1. 13 M). Product information CAS Number: 1553 56 6 Molecular Weight: 374. 56 Formula: C24H38O3 Synonym: Dehydrolithocholic acid 3 oxoLCA Chemical Name: (4R) 4 [(1R,3aS,3bR,5aR,9aS,9bS,11aR) 3a,3b,5a,9b tetrahydrogenio 9a,11a dimethyl 7 oxo hexadecahydro 1H