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E-7449 (10 μM) inhibits Wnt signaling in SW480 cells
Smiles: COC1=CC(F)=CC=C1C1=CC(NC2=CC(CS(C)(=N)=O)=CC=N2)=NC=C1F
IC50 value:Target:Astragaloside II and isoastragaloside I selectively increased adiponectin secretion in primary adipocytes without any obvious effects on a panel of other adipokines
and orally bioavailable GPR40 agonist
Ergoloid mesylates is used as a treatment for dementia and Alzheimer disease
Azithromycin hydrate psin E-7449 (10 μM) inhibits WntAzithromycin dihydrate is a protein translation inhibitor used for it's antibacterial properties. It is also known to inhibit the epithelila to mesenchymal transition and suppresses LPS stimulated production of pro inflammatory cytokines in macrophages. Product information CAS Number: 117772 70 0 Molecular Weight: 767. 00 Formula: C38H74N2O13 Synonym: CP62993 dihydrate CP 62993 dihydrate CP 62993 dihydrate Zithromax dihydrate Chemical Name: