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VR23 produced a synergistic effect in killing multiple myeloma cells
Smiles: C1SC2=CC=CC=C2C2NC3=CC=CC=C3C=21
CAS Number: 1792999-26-8
Smiles: O=C(NC1CCN(CC(F)(F)F)CC1)C1=CN=C(C=C1)C1=CC(F)=CC=C1
Formula: C14H17IN4O2
Masitinib Size:2mg solid VR23 produced a synergistic effectMasitinib, also known as AB1010, is an orally bioavailable and multi targeted protein tyrosine kinase inhibitor with potential antineoplastic activity. Masitinib selectively binds to and inhibits both the wild type and mutated forms of the stem cell factor receptor (c Kit; SCFR); platelet derived growth factor receptor (PDGFR); fibroblast growth factor receptor 3 (FGFR3); and, to a lesser extent, focal adhesion kinase (FAK). As a consequence, tumor