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Smiles: C#CCOCCOCCOCCOCCOCC(=O)ON1C(=O)CCC1=O
3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors
InChiKey: BQAVZGJJQFJSMW-UHFFFAOYSA-N
Smiles: CC1C2C(CC3C4CCC5CC(CCC5(C)C4CCC32C)OC2OC(CO)C(O)C(O)C2OC2OC(CO)C(O)C(O)C2O)OC=1CCC(C)COC1OC(CO)C(O)C(O)C1O
but had only a marginal effect in PC-12 cells and HL-60 cells
KL1333 011381 Smiles: C#CCOCCOCCOCCOCCOCC(=O)ON1C(=O)CCC1=OKL1333, a derivative of lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H: quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin induced ototoxicity in mouse cochlear cultures. Product information CAS Number: 1800405 30 4 Molecular Weight:
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