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G007-LK B-PS 57% of viruses with genotypes

SKU: 89073182288

4.1
USD90.00 USD115.00

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Description

57% of viruses with genotypes containing Y181C as a single NNRTI mutation (43% for efavirenz)

5R)-2-(4-aminopyrrolo[2

Epub 2015 Oct 5

InChiKey: ZBOYJODMIAUJHH-SANMLTNESA-N

Netarsudil/latanoprost fixed-dose combination for the treatment of open-angle glaucoma or ocular hypertension

G007-LK B-PS 57% of viruses with genotypesG007 LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1 2 inhibitor. G007 LK displayed high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice. G007 LK was first discovered by Dr. Stefan Krauss's team. Product information CAS Number: 1380672 07 0 Molecular Weight: 529. 96 Formula:

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