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PF-06840003 coglurant Chemical Name: 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2

SKU: 89027503499

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Description

Chemical Name: 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2

It is noteworthy that lipid levels are also reduced in treated animals

InChi: InChI=1S/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8

β-arrestin-1 and β-arrestin-2 recruitment

Oral delivery of SSR128129E (30 mg/kg/day

PF-06840003 coglurant Chemical Name: 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2PF 06840003 (EOS200271) is a highly selective orally bioavailable IDO 1 inhibitor with IC50s of 0. 41 M, 0. 59 M, and 1. 5 M for hIDO 1, dIDO 1, and mIDO 1, respectively. Product information CAS Number: 198474 05 4 Molecular Weight: 232. 21 Formula: C12H9FN2O2 Chemical Name: 3 (5 fluoro 1H indol 3 yl)pyrrolidine 2,5 dione Smiles: O=C1NC(=O)CC1C1=CNC2C=CC(F)=CC1=2 InChiKey: MXKLDYKORJEOPR UHFFFAOYSA N InChi: InChI=1S C12H9FN2O2 c13 6 1 2 10 7(3 6)9(5

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