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(S)-CFT7455 tinib bromide 8-tetrahydroquinazolin-4-amine

SKU: 88874675743

4.2
USD100.00 USD127.00

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Description

8-tetrahydroquinazolin-4-amine

InChi: InChI=1S/C19H17ClN2O5/c1-3-21-19(25)17-16(10-4-6-11(26-2)7-5-10)18(27-22-17)12-8-13(20)15(24)9-14(12)23/h4-9

colony and tumorosphere forming capability in TNBC cells

InChiKey: RYHCACJBKCOBTJ-UHFFFAOYSA-N

PR5-LL-CM01 inhibits NF-κB activation and its target gene expression in PDAC and CRC cells

(S)-CFT7455 tinib bromide 8-tetrahydroquinazolin-4-amine(S) CFT7455 is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader. (S) CFT7455 is an anti cancer agent that binds with high affinity to the cereblon E3 ligase (Kd of 0. 9 nM)(WO2022032132A1; Compound 1). Product information CAS Number: 2504235 67 8 Molecular Weight: 469. 53 Formula: C28H27N3O4 Smiles: O=C1CC[C@@H](C(=O)N1)N1C2=CC=C(CC3=CC=C(CN4CCOCC4)C=C3)C3=CC=CC(=C23)C1=O InChiKey: MUKCJOOKCZSQNW DEOSSOPVSA N

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