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59(8):4446-52
It works primarily through topoisomerase I inhibition
Jan Martin Berke
13-heptaen-10-yl}piperazin-1-yl)ethoxy]ethan-1-ol)
7 cells and mouse bone marrow-derived macrophages (BMMs) in a concentration-dependent manner
Rosiglitazone hydrochloride - CAS# 302543-62-0 Size:10mg solid 59(8):4446-52Rosiglitazone hydrochloride (BRL 49653 hydrochloride) is a selective, orally active PPAR agonist with EC50s of 30 nM, 100 nM and 60 nM for PPAR1, PPAR2, and PPAR, respectively. Rosiglitazone hydrochloride binds to PPAR with a Kd of approximately 40 nM. Rosiglitazone hydrochloride is also an activator of TRPC5 (EC50=~30 M) and an inhibitor of TRPM3. Product information CAS Number: 302543 62 0 Molecular Weight: 393. 89 Formula: C18H20ClN3O3S Synonym:
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