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Addition of 20-100 nM Hesperadin leading to loss of phosphorylation of the mitogenic histone H3 at the Ser10 site
InChiKey: XMEVHPAGJVLHIG-FMZCEJRJSA-N
Solubility: DMSO: 3 mg/mL(8
Anagrelide hydrochloride
Saunders E
UNC 0631 - CAS# 1320288-19-4 Size:Solid 2 mg Addition of 20-100 nM HesperadinUNC 0631 is a novel G9a inhibitor with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity. Protein lysine methyltransferase G9a plays key roles in the transcriptional repression of a variety of genes via dimethylation of lysine 9 on histone H3 (H3K9me2) of chromatin as well as dimethylation of nonhistone proteins including tumor suppressor p53. Product information CAS Number: 1320288 19 4
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