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Emricasan Catalog No.:M10978-10 is a next-generation proteasome inhibitor

SKU: 86746514735

4.5
USD108.90 USD135.90

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Description

is a next-generation proteasome inhibitor with demonstrated preclinical and clinical antimyeloma activity

MCT-14-0775

InChiKey: IIJDFXNUWZTHIM-NRFANRHFSA-N

InChiKey: LAZPBGZRMVRFKY-HNCPQSOCSA-N

26S)-3-[(1R)-2-carbamoyl-1-hydroxyethyl]-11

Emricasan Catalog No.:M10978-10 is a next-generation proteasome inhibitorEmricasan, also known as IDN 6556 and PF 03491390, is a first in class caspase inhibitor in clinical trials for the treatment of liver diseases. Emricasan (IDN 6556) decreases liver injury and fibrosis in a murine model of non alcoholic steatohepatitis. IDN6556 facilitates marginal mass islet engraftment in a porcine islet autotransplant model. Oral IDN 6556 may lower aminotransferase activity in patients with chronic hepatitis C. Orally administered

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