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shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A(2) through molecular docking
InChiKey: AZUQEHCMDUSRLH-UHFFFAOYSA-N
but not by ROCK1 or ROCK2
Molecular Weight: 1545
TCS 2510 (10 μM
KZR-504 1739 shows anti-inflammatory activity with evidenceKZR 504 is a highly selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2), with IC50s of 51 nM, 4. 274 M for LMP2 and LMP7, respectively. KZR 504 is of interest for the treatment of autoimmune disease. Product information CAS Number: 1629052 78 3 Molecular Weight: 413. 42 Formula: C21H23N3O6 Chemical Name: (2S) 3 hydroxy N [(2S) 1 [(2R) 2 methyloxiran 2 yl] 1 oxo 3 phenylpropan 2 yl] 2 [(6 oxo 1,6 dihydropyridin 2
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