ACHN-975 Catalog No.:M23886-C Smiles: CC1=CN(C=N1)C1=CC=C2C(=O)N(CCN2C1=O)[C@@H](C)[C@@H]1CC[C@@H](O1)C1=CC(F)=C(Cl)C=C1C(F)(F)F

Smiles: CC1=CN(C=N1)C1=CC=C2C(=O)N(CCN2C1=O)[C@@H](C)[C@@H]1CC[C@@H](O1)C1=CC(F)=C(Cl)C=C1C(F)(F)F

An unbound in vivo IC50 of 0

Smiles: CC(C)(C(=O)N[C@@H]1C2CC3CC1C[C@](C3)(C2)C(N)=O)N1CCN(CC1)C1=CC=C(C=N1)C(F)(F)F

WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKi of 8

GZD824 also displayed good oral bioavailability (48

ACHN-975 Catalog No.:M23886-C Smiles: CC1=CN(C=N1)C1=CC=C2C(=O)N(CCN2C1=O)[C@@H](C)[C@@H]1CC[C@@H](O1)C1=CC(F)=C(Cl)C=C1C(F)(F)FACHN 975 is a selective LpxC inhibitor and exhibits a subnanomolar LpxC inhibitory activity. ACHN 975 is against a wide range of gram negative bacterias with low MIC values (1 g mL). Product information CAS Number: 1410809 36 7 Molecular Weight: 369. 41 Formula: C20H23N3O4 Chemical Name: (2S) 3 amino N hydroxy 2 [(4 {4 [(1R,2R) 2 (hydroxymethyl)cyclopropyl]buta 1,3 diyn 1 yl}phenyl)formamido] 3 methylbutanamide Smiles: