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Tandospirone - CAS# 87760-53-0 Catalog No.:M10386-10 CAS Number: 502487-67-4

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Description

CAS Number: 502487-67-4

Thirty-six rats of either sex were divided into six groups (two control groups

Formula: C15H13F6N3O4S2

Smiles: CC(C)(C)C1C=CC(C=CC(=O)NC2=CC3OCCOC=3C=C2)=CC=1

Hamacher A

Tandospirone - CAS# 87760-53-0 Catalog No.:M10386-10 CAS Number: 502487-67-4Tandospirone citrate is a potent and selective 5 HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR 2, SR 1C, 1, 2, D1 and D2 receptors (Ki values ranging from 1300 41000 nM). IC50 Value: 275 nM(Ki) Target: 5 HT1Ain vitro: Tandospirone is most potent at the 5 HT1A receptor, displaying a Ki value of 27 + 5 nM. The agent is approximately two to three orders of magnitude less potent at 5 HT2, 5 HT1C, alpha 1 adrenergic, alpha 2

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