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Smiles: N#CC1=NC=CN=C1S(=O)(=O)C1=CC=CS1
01 for 1 mg/kg
Latanoprost acid (10 μM
1980 Jul-Aug
Bacteriochlorophyll
ZLJ-6 Size:Contact [email protected] for quotation Smiles: N#CC1=NC=CN=C1S(=O)(=O)C1=CC=CS1IC50: 0. 73, 0. 31, and 0. 99 M for COX 1, COX 2, and 5 LO, respectively ZLJ 6 is a dual inhibitor of COX and 5 lipoxygenase (5 LO). Cyclooxygenase (COX) is an enzyme that is responsible for formation of prostanoids, such as thromboxane and prostaglandins such as prostacyclin. 5 lipoxygenase (5 LO) is the major source of leukotrienes. In vitro: ZLJ 6 was identified as a potent inhibitor of cyclooxygenase in human whole blood. It also inhibited the
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