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GGTI-2418 14533 InChi: InChI=1S/C18H15NO4/c1-19(11-12-5-3-2-4-6-12)14-8-7-13-9-15(17(20)21)18(22)23-16(13)10-14/h2-10H

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Description

InChi: InChI=1S/C18H15NO4/c1-19(11-12-5-3-2-4-6-12)14-8-7-13-9-15(17(20)21)18(22)23-16(13)10-14/h2-10H

2017 Mar 22

The effects of intravenous ADP infusions of 2-8mg/kg/hour were examined in anesthetized Wistar rats that were untreated or chronically pretreated with clopidogrel

Chemical Name: potassium 4-{[(1R

3-benzodiazole-7-carboxylate

GGTI-2418 14533 InChi: InChI=1S/C18H15NO4/c1-19(11-12-5-3-2-4-6-12)14-8-7-13-9-15(17(20)21)18(22)23-16(13)10-14/h2-10HGGTI 2418 is a highly potent, competitive, and selective geranylgeranyltransferase I (GGTase I) inhibitor. GGTI 2418 inhibits GGTase I and FTase activities with IC50s of 9. 5 nM and 53 M, respectively. GGTI 2418 also increases p27(Kip1) and induces significant regression of breast tumors. Product information CAS Number: 501010 06 6 Molecular Weight: 441. 52 Formula: C23H31N5O4 Chemical Name: (2S) 2 {[(2S) 2 benzyl 4 [(5 methyl 1H imidazol 4 yl)methyl]

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