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NC[C@H]1OB(O)C2=C1C(Cl)=CC=C2OCCO
Smiles: N#C/C(=C\C1=CC=CC2=CN=CC=C12)/C1=CNC2=CC=CC=C12
InChi: InChI=1S/C14H20N2O4/c1-8(2)12(15)13(18)16-11(14(19)20)7-9-3-5-10(17)6-4-9/h3-6
Mocravimod hydrochloride (KRP-203) ameliorates atherosclerosis in LDL-R−/− Mice
Formula: C8H12O2
RORγt agonist 1 Catalog No.:M30089-C NC[C@H]1OB(O)C2=C1C(Cl)=CC=C2OCCORORt agonist 1 (compound 14) is a potent, orally bioavailable RORt agonist with an EC50 of 20. 8 nM. RORt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORt agonist 1 is a potential candidate of RORt agonist for cancer immunotherapy. Product information CAS Number: 2377378 89 5 Molecular Weight: 545. 45 Formula: C24H17F6NO5S Chemical Name: 2 {6 [3 (difluoromethoxy) 5 fluorophenyl] 1 [3